General Stability | Organism |
---|---|
divalent cations and 2-mercaptoethanol do not stabilize during purification | Homo sapiens |
lyophilization inactivates | Homo sapiens |
substrates stabilize during purification | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3,3-Dimethylbutyrate | competitive to betaine | Homo sapiens | |
Butyrate | moderate, competitive to betaine | Homo sapiens | |
Isovalerate | competitive to betaine | Homo sapiens | |
additional information | no inhibition by sarcosine | Homo sapiens | |
S-(delta-Carboxybutyl)-DL-homocysteine | - |
Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
45000 | - |
6 * 45000, SDS-PAGE | Homo sapiens |
270000 | - |
gel filtration | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Equus caballus | - |
- |
- |
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
two forms of the enzyme | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Homo sapiens | - |
kidney | - |
Equus caballus | - |
liver | - |
Homo sapiens | - |
liver | - |
Equus caballus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.314 | - |
- |
Homo sapiens |
Storage Stability | Organism |
---|---|
-20°C, over a year in 50% v/v glycerol | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N,N,N-trimethylglycine + L-homocysteine | - |
Homo sapiens | N,N-dimethylglycine + L-methionine | - |
? | |
N,N,N-trimethylglycine + L-homocysteine | - |
Equus caballus | N,N-dimethylglycine + L-methionine | - |
? |
Subunits | Comment | Organism |
---|---|---|
hexamer | 6 * 45000, SDS-PAGE | Homo sapiens |